伯乐ddSEQ Test Cartridges (12003862)

The ddSEQ Single-Cell Isolator is part of the Bio-Rad Single-Cell Next-Generation Sequencing (NGS) Solution, which works with the Bio-Rad SureCell ATAC-Seq Kit. The technology utilizes disposable microfluidic cartridges to coencapsulate single cells or single nuclei and barcoded beads into subnanoliter droplets, where cell-bead pairing and barcoding occur. ATAC-Seq libraries are subsequently prepared and sequenced, and analysis is conducted with the Bio-Rad Omnition Analysis Software.

Features and Benefits

Process hundreds to tens of thousands of cells per experiment

Sensitive and unbiased characterization of chromatin accessibility or transcriptional signatures

Scalable solution to accommodate a wide range of experimental designs

Agnostic to mammalian cell size, enabling unbiased profiling of diverse cell populations

End-to-end single-cell sequencing solution with simple, powerful data analysis

Applications and Uses

Assess cell-to-cell heterogeneity and identify new sub-populations

Map genome-wide chromatin accessibility

Dissect transcriptional mechanics

Infer gene regulatory networks

Neurology research — normal brain function, neurological disease and psychological disorders

Immunology research — B Cell and T Cell characteristic and functional analyses

Cancer research — cellular expansion of clonal cells in tumors and mutations that lead to differences in gene expression and drug response

Stem cell research — cell fate, cell development and differentiation, including reverse engineering tissues

Included Components

ddSEQ Test Cartridges (12003862)

ddSEQ Cartridge Holder (12004739)

ddSEQ Single-Cell Isolator (12004336)

Power supply and power cord

User manual and product documentation